You can find these new videos on the Showcase page in the Stem Cells category, and also visit them at WEHI by clicking on each of the screenshots below.
Breast Stem Cells An overview of the human mammary gland with a focus on the role of breast stem cells during pregnancy. The primary function of the mammary gland is to produce milk to nourish young offspring. The mammary gland is comprised of three main cell types; alveolar, ductal and myoepithelial cells. During pregnancy, the mammary gland increases in size due to the action of breast stem cells, which can mature into any of the three mammary gland cell types.
The Control of Breast Stem Cells This animation illustrates how breast stem cells respond to steroid hormone despite the cells not having any steroid receptors. The animation illustrates the research published in Nature (Vol 465, Issue 7299, 2010) by the laboratory of Jane Visvader and Geoffrey Lindeman.
The Origin of Breast Cancer This animation visualises research published in Nature Medicine (Vol 15, Issue 8, 2009) by the laboratory of Jane Visvader and Geoffrey Lindeman. The mammary gland is comprised of three main cell types; alveolar, ductal and myoepithelial cells. Breast stem cells can develop into any of the three cell types through a series of intermediate cell stages. One intermediate is the luminal progenitor cell, which develops into either alveolar or ductal cells. The paper describes how an aberrant form of a luminal progenitor cell is involved in the development of some forms of breast cancer.